Journal: iScience
Article Title: MFAP5 + synovial fibroblasts drive LOX upregulation to promote osteoarthritis progression
doi: 10.1016/j.isci.2026.116286
Figure Lengend Snippet: LOX inhibitor improves MIA-induced joint damage (A) Representative images of H&E staining of rat joint tissues across four groups. Scale bars, 200 μm, n = 4. (B) Picrosirius red staining images of rat joint tissues across four groups. Scale bars, 100 μm. (C–F) Immunohistochemistry of LOX, IL-1β, MFAP5, and FBN1, rat joint tissues across four groups. IOD, integrated optical density. Scale bars, 400 μm, n = 4. Data were presented as mean ± SEM. Statistical significance was calculated using one-way ANOVA followed by Tukey’s multiple comparisons test (A and C–F). ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001.
Article Snippet: Picrosirius red staining Kit , Servicebio , Cat# G1078.
Techniques: Staining, Immunohistochemistry